NanoBrook Series

NanoBrook Series

Characterizing proteins, nanoparticles, & polymers confronts users with a difficult choice of instrumentation. Brookhaven Instruments makes that choice easier with its highly configurable NanoBrook series of products.

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Description

The NanoBrook Series is a Configurable Platform for Particle Sizing and Zeta Potential Measurements

The NanoBrook Series size and zeta potential analyzers incorporate all you need for fast, routine, sub-micron measurements of size and zeta potential. Based on the principles of Dynamic Light Scattering (DLS) for particle sizing and distribution, and based on doppler velocimetry (electrophoretic light scattering or ELS) for zeta potential measurement, most measurements only take a minute or two. The instrument also includes Phase Analysis Light Scattering (PALS) measurements for samples with low mobilities.

Rapid, Reliable, and Accurate Analysis

The NanoBrook Series particle size and zeta potential analyzers are based on the principles of Dynamic Light Scattering (DLS) for particle sizing and distribution, and based on doppler velocimetry (electrophoretic light scattering, ELS) for zeta potential measurement. Most measurements only take a minute or two. These instruments can also be configured with Phase Analysis Light Scattering (PALS) for samples with low mobilities or high conductivity measurements.

Three Possible Scattering Angles

Measurements of colloids are traditionally made using a 90° scattering angle. For smaller nanoparticles, proteins including IgG, mAbs, and peptides, these < 50 nm samples can be measured using the backscattering angle (173°). Finally the 15° detection angle can be selected for added sensitivity with aggregation measurements. Zeta potential measurements are always performed using the 15° detection angle to minimize diffusion broadening.

The NanoBrook Omni combines all of the most common configurations

With the NanoBrook Omni, measure samples in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and aqueous solutions. Particle and protein sizing, with the highest sensitivity, utilize three measurement angles for truly unbiased measurement results.

Rapid, Reliable, and Accurate Analysis

Characterizing proteins, nanoparticles, and polymers confronts the user with a difficult choice of instrumentation. Brookhaven Instruments makes that choice easier with the NanoBrook series of instruments. Choose from particle sizing including backscatter for proteins, Zeta Potential, or combinations including molecular weight determination of small polymers and proteins.

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